Hello, I'm trying to read a sequence from a textfile has a size of around 3gigabytes based on the tutorial to import millions of sequences. For files bigger than around 1.5gig the program of the tutorial immediately stops because open(multiSeqFile.concat, argv[1], OPEN_RDONLY) returns false. For file(s) (since i only tested it with one file) bigger than around 700mb the program crashs on an invalid null pointer after a while. What are the limitations here? I'm running this on a win7 64 machine with 4gig of ram. The program is compiled in visual studio 2010 Is there a better way to do this? Since i'm not trying to read multiple sequences but only one that is very large. Thanks, Johannes |