Hello everyone, I have trouble installing SeqAn on a RHEL system, where I installed the zlib and boost libraries manually. My folder structure looks the following: {TARGET_DIR}/bin -> preferred build directory {TARGET_DIR}/doc {TARGET_DIR}/include/boost/ -> contains all the boost subfolders .hpp files etc. {TARGET_DIR}/lib -> contains libboost* and libz* {TARGET_DIR}/seqan-trunk -> as checked out from SVN {TARGET_DIR}/share Following the tutorial (trac.seqan.de/wiki/Tutorial/GettingStarted/LinuxMakefiles), from the {TARGET_DIR}/bin folder I call cmake ../seqan-trunk -DCMAKE_BUILD_TYPE=Release, which succeeds. Then >make Make fails at approximately 5% having trouble to find the boost math libraries while installing snp_store. The (potentially crucial part of the) environment looks like this: {TARGET_DIR}/bin$ env | grep CMAKE CMAKE_MAN_DIR=/opt/.../.../cmake/2.8.6/man CMAKE_DOC_DIR=/opt/.../.../cmake/2.8.6/doc CMAKE_LIBRARY_PATH={TARGET_DIR}/lib CMAKE_BIN_DIR=/opt/.../.../cmake/2.8.6/bin CMAKE_HOME=/opt/.../.../cmake/2.8.6 DCMAKE_INCLUDE_PATH={TARGET_DIR}/include CMAKE_VERSION=2.8.6 CMAKE_INCLUDE_PATH={TARGET_DIR}/include {TARGET_DIR}/bin$ env | grep LIBR CMAKE_LIBRARY_PATH={TARGET_DIR}/lib LD_LIBRARY_PATH={TARGET_DIR}/lib {TARGET_DIR}/bin$ env | grep INCLUDE DCMAKE_INCLUDE_PATH={TARGET_DIR}/include CMAKE_INCLUDE_PATH={TARGET_DIR}/include INCLUDE={TARGET_DIR}/include The error looks the following and produces many more lines of errors: [ 5%] Building CXX object core/apps/snp_store/CMakeFiles/snp_store.dir/snp_store.cpp.o In Datei, eingefügt von {TARGET_DIR}/seqan-trunk/core/apps/snp_store/snp_store.cpp:53: {TARGET_DIR}/seqan-trunk/core/apps/snp_store/snp_store.h:36:40: Fehler: boost/math/distributions.hpp: Datei oder Verzeichnis nicht gefunden However the file{TARGET_DIR}> ls include/boost/math/distributions.hpp include/boost/math/distributions.hpp DOES exist. It is just not found. What am I doing wrong? Any help would be greatly appreciated. Thank you very much, Nomi