Re: [Seqan-dev] Realigning over Amino Acids
On 29.10.2016 03:18, Gregory Burgess wrote:
> Hi,
>
> I'm using seqan 1.4.1. I have a fasta file of aligned (gap characters
> included) amino acid sequences. I would like to simply read in this
> file and use seqan's realign function over these sequences.
>
> I see that realign() requires a Fragment Store, but I'm not sure how to
> generate the appropriate data structures from already-aligned amino acid
> sequences. Can someone provide a general outline of this (or another
> approach)?
>
> Thanks,
> Greg
Dear Greg,
SeqAn-1.4.1 is not developed anymore (since quite some time now). Please
reproduce your problem with a current release and open an issue on
github.com/seqan/seqan if the problem persists.
If you don't want to use the fragment store I would recommend reading
the alignment into an AlignmentGraph and then call globalAlignment() on
that, possibly with a small band if performance is important.
Best regards,
Hannes
--
Hannes Hauswedell
PhD student
Max Planck Institute for Molecular Genetics / Freie Universität Berlin
address Institut für Informatik
Takustraße 9
Room 019
14195 Berlin
telephone +49 (0)30 838-75241
fax +49 (0)30 838-75218
e-mail hannes.hauswedell@[molgen.mpg.de|fu-berlin.de]