Am Sonntag, 19. April 2015, 23:16:59 schrieb Y Z: > Dear whom may concern, > > I followed the Mini Botie tutorial to build a BWT index for human genome > reference (hg38). > TIndex fmIndex(text); > TIter it(fmIndex); > search(it, fragStore.readSeqStore); > save(fmIndex, ...); > > However, after about 570 minutes, the program crashed with the message: > Asynchronous I/O operation failed (waitFor with timeOut=0ms) "Success" > fildes: 4 > ".../include/seqan/file/file_page.h:842 FAILED! (writing operation could > not be completed: "Success") This is an indicator for you running out of space in your temporary directory. You can change your temporary directory by setting the TMPDIR environment variable! Hope that helps, -- Hannes Hauswedell PhD student Max Planck Institute for Molecular Genetics / Freie Universität Berlin address Institut für Informatik Takustraße 9 Room 019 14195 Berlin telephone +49 (0)30 838-75241 fax +49 (0)30 838-75218 e-mail hannes.hauswedell@[molgen.mpg.de|fu-berlin.de]